Actin was used as a loading control; CC, cold oligonucleotide competitor; NS, non-specific binding. Because the MSA-supplemented osteoblasts produced a reduced inflammatory response to BCCM, we tested if the effect was related to the level of GPx activity, which in turn, affects intracellular oxidative stress. Several reports indicate that bone tissues in humans are affected by Se 36
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Selenium Effective In Breast Cancer Treatment, According to Study
Bisphosphonates and breast carcinoma: Bjornstedt M, et al. Models, mechanisms and clinical evidence for cancer dormancy. These data indicated that MSA might be acting through short-lived metabolites as reported by others
Clinical trials are looking at the possible role of selenium in reducing the risk of breast cancer. Food sources of selenium include Brazil nuts, seafood, cereals, and grains. Comparison with bone histomorphometry. The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.